I was playing around with the scope today trying to see if I can replicate the error. Turns out it has something to do with having both cameras (main and guide) and tracking running simultaneously. If the guide cam is looping and the main camera is taking pics rapidly, it's more likely to hit the error quickly.
I'm wondering if it has something to do with saturation/congestion on the USB? I rearranged the USB plugs so that the cameras each get their own USB 3 port. Seems to working better?