But this goes back to what I was rambling about last night. I'm sure these techniques would work to some degree, but I have no idea whether it's any better than the calibration with dark and bias frames that #astrophotography people do normally. Like, it might be a neat trick, but it will always be easier, more pragmatic, and produces better results to just buy a cooled sensor camera and build a darks library, even if it is more boring.
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